Article
Further linkage evidence for localization of mutational sites for nonsyndromic types of X-linked mental retardation at the pericentromeric region.
American journal of medical genetics - 12 Jul 1996
Robledo R, Melis P, Laficara F, Marchi J, Rinaldi A, Siniscalco M, Filippi G
Abstract excerpt
We used several microsatellite markers scattered along the X chromosome to search for linkage relationships in a large Sardinian pedigree segregating for nonspecific X-linked mental retardation (MRX). Markers DXS573 and AR, located at chromosomal subregions Xp11.4-p11.22 and Xq11.2-q12, respectiv...
Topics
- Chromosome Mapping
- Female
- Genetic Carrier Screening
- Genetic Linkage
- Humans
- Intellectual Disability
- Male
- Mutation
- Pedigree
- Recombination, Genetic
- X Chromosome