Article
Human Y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11.
Human molecular genetics - 1 Jul 1996
Vogt P H, Edelmann A, Kirsch S, Henegariu O, Hirschmann P, Kiesewetter F, Köhn F M, Schill W B, Farah S, Ramos C, Hartmann M, Hartschuh W, Meschede D, Behre H M, Castel A, Nieschlag E, Weidner W, Gröne H J, Jung A, Engel W, Haidl G
Abstract excerpt
In a large collaborative screening project, 370 men with idiopathic azoospermia or severe oligozoospermia were analysed for deletions of 76 DNA loci in Yq11. In 12 individuals, we observed de novo microdeletions involving several DNA loci, while an additional patient had an inherited deletion. They were mapped to three different subregions in Yq11. One subregion coincides to the AZF region defined recently in...
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