Article
A novel DnaJ-like protein in Escherichia coli inserts into the cytoplasmic membrane with a type III topology.
Molecular microbiology - 1 Jun 1996
Clarke D J, Jacq A, Holland I B
Abstract excerpt
We describe a novel Escherichia coli protein, DjlA, containing a highly conserved J-region motif, which is present in the DnaJ protein chaperone family and required for interaction with DnaK. Remarkably, DjlA is shown to be a membrane protein, localized to the inner membrane with the unusual Type III topology (N-out, C-in). Thus, DjlA appears to present an extremely short N-terminus to the periplasm and has a...
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