Article
Structure of the human laminin gamma 2 chain gene (LAMC2): alternative splicing with different tissue distribution of two transcripts.
Genomics - 15 Feb 1996
Airenne T, Haakana H, Sainio K, Kallunki T, Kallunki P, Sariola H, Tryggvason K
Abstract excerpt
We have determined the structure of the human laminin gamma 2 chain gene (LAMC2), which is mutated in some patients with junctional epidermolysis bullosa. Eight lambda phage clones isolated from a genomic library and three subgenomic lambda phage clones made from a plasmid artificial chromosome c...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA
- Epidermolysis Bullosa, Junctional
- Exons
- Female
- Gene Expression Regulation, Developmental
- Humans
- In Situ Hybridization
- Infant, Newborn
- Introns
- Laminin
- Molecular Sequence Data
- Mutation
- Pregnancy
- RNA, Complementary