Article
Cystic fibrosis: basic chemical and cellular mechanisms.
British journal of hospital medicine - 1 Jan 2000
Stern M, Geddes D
Abstract excerpt
Cystic fibrosis (CF) primarily affects epithelial-lined organs, the most important being the lungs. Much of the known pathogenesis of the disease has been elucidated by the identification of the gene mutated in CF which encodes the cystic fibrosis transmembrane conductance regulator, a chloride c...
Topics
- Chloride Channels
- Chromosomes, Human, Pair 7
- Cystic Fibrosis
- Epithelium
- Humans
- Intestinal Mucosa
- Mutation
- Respiratory System
