Article
[Myotonin protein kinase].
Rinsho shinkeigaku = Clinical neurology - 1 Dec 1995
Ishiura S, Sasagawa N, Saitoh N, Koike H, Sorimachi H, Suzuki K, Shimokawa M, Usuki F, Nakase H, Kamakura K
Abstract excerpt
The mutation underlying myotonic dystrophy is the expansion of polymorphic CTG repeat in the 3'-noncoding region of the myotonin protein kinase (MtPK) gene mapping to chromosome 19q13.3. A full-length cDNA of human MtPK was cloned and expressed in COS-1 cells. MtPK is recovered from the COS cell...
Topics
- Chromosomes, Human, Pair 19
- DNA
- Humans
- Mutation
- Myotonic Dystrophy
- Myotonin-Protein Kinase
- Protein Kinases
- Protein Serine-Threonine Kinases
- Trinucleotide Repeats