Article
[Protein and DNA sequencing analyses of transthyretin in familial amyloidotic polyneuropathy].
Rinsho shinkeigaku = Clinical neurology - 1 Dec 1995
Nakazato M
Abstract excerpt
Recent advances in protein chemistry and the molecular biology of amyloid proteins have led to knowledge of the primary etiology of FAP. The protein product of the gene in question was identified, then the chromosomal location and point mutations in the gene were determined. Diagnosis of the diso...
Topics
- Amyloid Neuropathies
- Animals
- DNA
- Genetic Variation
- Humans
- Mass Spectrometry
- Mice
- Prealbumin
- Sequence Analysis, DNA