Article
Schwann cell tumors express characteristic patterns of CD44 splice variants.
Journal of neuro-oncology - 1 Dec 1995
Sherman L, Skroch-Angel P, Moll J, Schwechheimer K, Ponta H, Herrlich P, Hofmann M
Abstract excerpt
Members of the CD44 family of cell surface hyaluronate-binding proteins have been implicated in cell migration, cell-matrix interactions and tumor progression. To determine whether these proteins might play a role in the normal functions of Schwann cells and in their tumorigenesis, we examined th...
Topics
- Alternative Splicing
- Animals
- Base Sequence
- Cell Line
- DNA Primers
- Flow Cytometry
- Ganglia, Spinal
- Gene Expression
- Genetic Variation
- Humans
- Hyaluronan Receptors
- Hyaluronic Acid
- Immunohistochemistry
- Molecular Sequence Data
- Neurilemmoma
- Peripheral Nerves
- Polymerase Chain Reaction
- Rats
