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Article

G542X mutation in Mexican cystic fibrosis patients.

Clinical genetics - 1 Jan 1996

Villarreal M T, Chávez M, Lezana J L, Cuevas F, Carnevale A, Códova E, del Angel R M, Orozco L

Abstract excerpt

We analyzed the frequency of the G542X mutation in a sample of 76 Mexican cystic fibrosis patients and the genotype-phenotype correlation. The mutation was screened using PCR-mediated site-directed mutagenesis, and was present on 7.2% of the CF chromosomes. This frequency is significantly higher than the worldwide frequency according to the Cystic Fibrosis Genetic Analysis Consortium (3.4%, p < 0.01), and similar...

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Identifiers

PMID: 8721574
DOI: 10.1111/j.1399-0004.1996.tb04326.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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