Molecular studies of translocations and trisomy involving chromosome 13.

doi:10.1002/(SICI)1096-8628(19960111)61:2<158::AID-AJMG11>3.0.CO;2-T

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Article

Molecular studies of translocations and trisomy involving chromosome 13.

American journal of medical genetics - 11 Jan 1996

Robinson W P, Bernasconi F, Dutly F, Lefort G, Romain D R, Binkert F, Schinzel A A

Abstract excerpt

Twenty-four cases of trisomy 13 and one case with disomy 13, but a de novo dic(13,13) (p12p12) chromosome, were examined with molecular markers to determine the origin of the extra (or rearranged) chromosome. Twenty-one of 23 informative patients were consistent with a maternal origin of the extr...

Topics

Adult
Alleles
Chromosomes, Human, Pair 13
Female
Humans
Infant, Newborn
Karyotyping
Male
Polymerase Chain Reaction
Translocation, Genetic
Trisomy

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