Article
Excessive homoplasy in an evolutionarily constrained protein.
Proceedings. Biological sciences - 22 Apr 1996
Wells R S
Abstract excerpt
The evolution of monomorphic proteins among closely related species has not been examined in detail. To investigate this phenomenon, the glycerol-3-phosphate dehydrogenase (Gpdh) locus was sequence in a broad range of Drosophila species. Although purifying selection to remove amino acid variation is the dominant force in the evolution of Gpdh, some replacements have occurred. The sequences were compared in the...
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