Article
High prevalence of human papillomavirus in squamous cell carcinoma and matched normal esophageal mucosa: assessment by polymerase chain reaction.
Cancer - 1 Nov 1995
Fidalgo P O, Cravo M L, Chaves P P, Leitão C N, Mira F C
Abstract excerpt
BACKGROUND: Studies using DNA technology have reported the presence of human papillomavirus (HPV) DNA in esophageal carcinomas, suggesting that it could play a role in the pathogenesis of this tumor. In the present study, in addition to DNA from neoplasms, normal mucosa was screened for viral DNA, assuming that this would increase HPV detection substantially. METHODS: Seventeen patients with esophageal carcinoma...
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