Homologous association of oppositely imprinted chromosomal domains.

doi:10.1126/science.272.5262.725

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Article

Homologous association of oppositely imprinted chromosomal domains.

Science (New York, N.Y.) - 3 May 1996

LaSalle J M, Lalande M

Abstract excerpt

Human chromosome 15q11-q13 encompasses the Prader-Willi syndrome (PWS) and the Angelman syndrome (AS) loci, which are subject to parental imprinting, a process that marks the parental origin of certain chromosomal subregions. A temporal and spatial association between maternal and paternal chromo...

Topics

Alleles
Angelman Syndrome
Chromosomes, Human, Pair 15
DNA
DNA Probes
Genomic Imprinting
Humans
In Situ Hybridization, Fluorescence
Methylation
Microscopy, Confocal
Prader-Willi Syndrome
S Phase
T-Lymphocytes
Transcription, Genetic

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