Article
Homologous association of oppositely imprinted chromosomal domains.
Science (New York, N.Y.) - 3 May 1996
LaSalle J M, Lalande M
Abstract excerpt
Human chromosome 15q11-q13 encompasses the Prader-Willi syndrome (PWS) and the Angelman syndrome (AS) loci, which are subject to parental imprinting, a process that marks the parental origin of certain chromosomal subregions. A temporal and spatial association between maternal and paternal chromosomes 15 was observed in human T lymphocytes by three-dimensional fluorescence in situ hybridization. This association...
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