Article
Assignment of FGF8 to human chromosome 10q25-q26: mutations in FGF8 may be responsible for some types of acrocephalosyndactyly linked to this region.
Genomics - 1 Nov 1995
White R A, Dowler L L, Angeloni S V, Pasztor L M, MacArthur C A
Abstract excerpt
Emerging evidence suggests that Fgf8, a recently identified member of the fibroblast growth factor family, plays an important role in outgrowth and patterning of the face, limbs, and central nervous system of the vertebrate embryo. We report the mapping of FGF8 to human chromosome 10q25-q26, usin...
Topics
- Acrocephalosyndactylia
- Animals
- Blotting, Southern
- Chromosomes, Human, Pair 10
- Cricetinae
- Fibroblast Growth Factor 8
- Fibroblast Growth Factors
- Growth Substances
- Humans
- Hybrid Cells
- Mice
- Mutation
- Neoplasm Proteins