Increasing Severity of Invasive Group A Streptococcal Disease in Australia: Clinical and Molecular Epidemiological Features and Identification of a New Virulent M-Nontypeable Clone

Abstract excerpt

We conducted a 12-year review of all cases of group A streptococcal (GAS) bacteremia that were seen at Royal Children's Hospital in Melbourne, Australia, from 1982 through 1993. Forty-two cases were identified. There was a trend towards increased incidence of infections, as well as a clear increase in their severity, during the study period; more previously healthy children were affected during the last 6 years...

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