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Article

Characterization of pra, a gene for replication control in pSAM2, the integrating element of Streptomyces ambofaciens.

Molecular microbiology - 1 Aug 1995

Sezonov G, Hagège J, Pernodet J L, Friedmann A, Guérineau M

Abstract excerpt

pSAM2 is a genetic element found integrated in Streptomyces ambofaciens (B2) and additionally in a replicating form in two mutants B3 and B4. The presence of the pSAM2 replicating form in these mutants was the result of mutations located on pSAM2 in the pra locus, named pra3 and pra4, respectively. The pra gene is not directly involved in replication, but its inactivation led to the disappearance of the pSAM2...

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PMID: 8559072
DOI: 10.1111/j.1365-2958.1995.mmi_17030533.x

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