Article
Complex behavior of simple repeats: the fragile X syndrome.
Pediatric research - 1 Nov 1995
Oostra B A, Halley D J
Abstract excerpt
The fragile X syndrome of mental retardation is one of the most common genetic diseases. The mutation causing this disease was the first of a new class of mutations involving repeat sequences disturbing gene function. Fragile X mutations consist of an expansion of a CGG trinucleotide repeat in th...
Topics
- Animals
- Disease Models, Animal
- Forecasting
- Fragile X Mental Retardation Protein
- Fragile X Syndrome
- Gene Amplification
- Humans
- Mutation
- Nerve Tissue Proteins
- RNA-Binding Proteins
- Repetitive Sequences, Nucleic Acid