Article
Hepatitis C virus genotype in patients with essential mixed cryoglobulinaemia.
QJM : monthly journal of the Association of Physicians - 1 Nov 1995
Sinico R A, Ribero M L, Fornasieri A, Renoldi P, Zhou J, Fasola M, Portera G, Arrigo G, Gibelli A, D'Amico G
Abstract excerpt
We studied 54 patients with essential mixed cryoglobulinaemia (EMC), (23 males, 31 females) mean age 61 years (range 28-77). Forty-one (76%) had type II cryoglobulinaemia and 13 (24%) type III. Antibodies to HCV were detectable by second-generation ELISA in 49 patients (91%) with confirmed or indeterminate RIBA results. HCV RNA was detected by RT PCR using 5' UTR nested primers; HCV genotypes 1a, 1b, 2 and 3a...
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