Diagnosis of sex in preimplantation embryos by fluorescent in situ hybridisation.

Abstract excerpt

The aim of prenatal genetic diagnosis is to give parents the option of terminating affected pregnancies. For most X linked conditions specific diagnosis is not possible and the only option is induced abortion of all male fetuses, of which half would be unaffected. An altemative is offered by preimplantation diagnosis of sex in embryos obtained by in vitro fertilisation and selective transfer of female embryos....

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