Article
von Willebrand factor mutation enhancing interaction with platelets in patients with normal multimeric structure.
The Journal of clinical investigation - 1 May 1993
Holmberg L, Dent J A, Schneppenheim R, Budde U, Ware J, Ruggeri Z M
Abstract excerpt
Variant von Willebrand disease designated as type I New York or type Malmö is characterized by enhanced ristocetin-induced platelet agglutination with normal von Willebrand factor multimeric distribution in plasma. We have studied four such patients belonging to three unrelated families and found...
Topics
- Adult
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Blood Platelets
- CHO Cells
- Codon
- Cricetinae
- DNA
- Exons
- Female
- Humans
- Introns
- Leucine
- Male
- Middle Aged
- Molecular Sequence Data