The Kallmann's syndrome variant (KSV) model of the schizophrenias.

Abstract excerpt

The KSV model of the schizophrenias proposes that up to 70% of schizophrenics have a pathogenic allele, or abnormal expression, of the KALIG-1 gene which is located at Xp22.3. This gene encodes a nerve-cell adhesion molecule (N-CAM) like protein, and is deleted in 66% of patients with Kallmann's syndrome, anosmia with secondary hypogonadism. Although superficially distinct, the schizophrenias and Kallmann's...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alleles
• Share to Cell Adhesion Molecules, Neuronal
• Share to Chromosome Deletion