A yeast expression system for human galactose-1-phosphate uridylyltransferase.

doi:10.1073/pnas.90.2.398

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Article

A yeast expression system for human galactose-1-phosphate uridylyltransferase.

Proceedings of the National Academy of Sciences of the United States of America - 15 Jan 1993

Fridovich-Keil J L, Jinks-Robertson S

Abstract excerpt

Galactose-1-phosphate uridylyltransferase (GALT) (UTP: alpha-D-hexose-1-phosphate uridylyltransferase, EC 2.7.7.10) is an essential enzyme of the Leloir pathway of galactose metabolism. Mutations in human GALT are associated with the potentially lethal disorder galactosemia, which affects 1 in 30...

Topics

Base Sequence
Galactosemias
Genes, Fungal
Genetic Complementation Test
Genetic Vectors
Hematopoietic Stem Cells
Humans
Lymphocytes
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Saccharomyces cerevisiae
Transfection
Transformation, Genetic
UTP-Hexose-1-Phosphate Uridylyltransferase

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Identifiers

PMID: 8421669
DOI: 10.1073/pnas.90.2.398
PMCID: PMC45669

Genes

GALT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8421669-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

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