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Article

Distribution of VP4 gene alleles in human rotaviruses by using probes to the hyperdivergent region of the VP4 gene.

Journal of clinical microbiology - 1 Jul 1993

Steele A D, Garcia D, Sears J, Gerna G, Nakagomi O, Flores J

Abstract excerpt

The rotavirus VP4 protein elicits the production of neutralizing antibodies and is known to play a role in inducing resistance to disease. At least five human rotavirus VP4 gene alleles have been described on the basis of antigenic polymorphism and/or nucleotide sequence differences. In the present study, we developed cDNA probes directed at the hyperdivergent region of the VP4 gene of the five described human...

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Identifiers

PMID: 8394374
DOI: 10.1128/jcm.31.7.1735-1740.1993
PMCID: PMC265623

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