Article
Distribution of VP4 gene alleles in human rotaviruses by using probes to the hyperdivergent region of the VP4 gene.
Journal of clinical microbiology - 1 Jul 1993
Steele A D, Garcia D, Sears J, Gerna G, Nakagomi O, Flores J
Abstract excerpt
The rotavirus VP4 protein elicits the production of neutralizing antibodies and is known to play a role in inducing resistance to disease. At least five human rotavirus VP4 gene alleles have been described on the basis of antigenic polymorphism and/or nucleotide sequence differences. In the prese...
Topics
- Alleles
- Base Sequence
- Capsid
- Capsid Proteins
- DNA Probes
- DNA, Viral
- Europe
- Genes, Viral
- Humans
- Latin America
- Molecular Probe Techniques
- Molecular Sequence Data
- Polymerase Chain Reaction
- Rotavirus
- Sensitivity and Specificity