Exclusion of the neurofibromatosis 1 locus in a family with inherited café-au-lait spots.

doi:10.1002/ajmg.1320460428

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Article

Exclusion of the neurofibromatosis 1 locus in a family with inherited café-au-lait spots.

American journal of medical genetics - 1 Jun 1993

Brunner H G, Hulsebos T, Steijlen P M, der Kinderen D J, vd Steen A, Hamel B C

Abstract excerpt

We have performed linkage analysis in a small family with autosomal dominant inheritance of multiple café-au-lait spots (CLS) in order to clarify its relationship to classical von Recklinghausen disease (NF 1). We found that an affected woman had transmitted a different haplotype for markers flan...

Topics

Adolescent
Alleles
Child
Chromosome Mapping
Female
Genes, Neurofibromatosis 1
Genetic Linkage
Humans
Mutation
Neurofibromatoses
Pedigree
Pigmentation Disorders

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