Case-control study of congenital anomalies in children of cancer patients.

Abstract excerpt

OBJECTIVES: To determine whether the offspring of cancer survivors are at an increased risk of congenital anomalies and whether cancer therapy before conception is associated with such an increase. DESIGN: Case-control study using computerised record linkage. SETTING: Ontario, Canada. SUBJECTS: Parents of children born during April 1979 to December 1986 who had a congenital anomaly diagnosed within the first year...

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