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Article

[A sporadic case of late onset familial amyloidotic polyneuropathy preceded by cardiac involvement].

Rinsho shinkeigaku = Clinical neurology - 1 Aug 1993

Aoki K, Koike R, Yuasa T, Ikeda S, Tsuji S

Abstract excerpt

We report a 65-year-old man with amyloidotic polyneuropathy, who first suffered from heart failure at the age of 57, 3 years before the onset of neurological symptoms. He had no obvious family history. We analysed the transthyretin gene of the patient and 6 asymptomatic family members using polymerase chain reaction (PCR). The single amino acid substitution of a methionine for valine at position 30, which is a...

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Source

Identifiers

PMID: 8261706

Genes

FAP
TTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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