Article
Linkage analysis of idiopathic generalised epilepsy in families of probands with Juvenile Myoclonic Epilepsy and marker loci in the region of EPM 1 on chromosome 21 q: Unverricht-Lundborg disease and JME are not allelic variants.
Neuropediatrics - 1 Feb 1994
Rees M, Curtis D, Parker K, Sundqvist A, Baralle D, Bespalova I N, Burmeister M, Chung E, Gardiner R M, Whitehouse W P
Abstract excerpt
The locus for Unverricht-Lundborg disease, EPM 1, has recently been mapped to chromosome 21q22.3. A locus, EJM 1, predisposing to idiopathic generalised epilepsy in families of probands with juvenile myoclonic epilepsy has been localised to chromosome 6p by evidence of linkage to the HLA region....
Topics
- Adolescent
- Aged
- Alleles
- Autoradiography
- Child
- Chromosome Aberrations
- Chromosome Disorders
- Chromosomes, Human, Pair 21
- Epilepsies, Myoclonic
- Epilepsy, Generalized
- Genetic Linkage
- Genetic Markers
- Genome, Human