Three unrelated cases of paracentric inversions of 1p in individuals with abnormal phenotypes.

doi:10.1002/ajmg.1320490412

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Article

Three unrelated cases of paracentric inversions of 1p in individuals with abnormal phenotypes.

American journal of medical genetics - 15 Feb 1994

Estop A M, Bansal V, Lin A, Levinson F, Karlin S M, Surti U, Wenger S L, Steele M W

Abstract excerpt

Paracentric inversions, involving a rearrangement within one chromosome arm, are rare. Although carriers of balanced paracentric inversions should theoretically not be at risk for abnormal offspring, such cases have been reported. We report on 2 unrelated cases of inherited paracentric inversions...

Topics

Abnormalities, Multiple
Cells, Cultured
Child, Preschool
Chromosome Fragility
Chromosome Inversion
Chromosomes, Human, Pair 1
Humans
Infant
Infant, Newborn
Male
Phenotype
Twins, Monozygotic

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