Coexistence of hereditary spherocytosis (HS) due to band 3 deficiency and beta-thalassaemia trait: partial correction of HS phenotype.

doi:10.1111/j.1365-2141.1993.tb03347.x

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Article

Coexistence of hereditary spherocytosis (HS) due to band 3 deficiency and beta-thalassaemia trait: partial correction of HS phenotype.

British journal of haematology - 1 Nov 1993

Miraglia del Giudice E, Perrotta S, Nobili B, Pinto L, Cutillo L, Iolascon A

Abstract excerpt

A kindred with hereditary spherocytosis and beta-thalassaemia trait was identified. Detailed studies of the red cell membrane proteins on polyacrylamide gels with sodium dodecyl sulphate (SDS-PAGE) demonstrated the presence of band 3 (anion transporter) deficiency in all HS subjects (20-25% reduc...

Topics

Adult
Anion Exchange Protein 1, Erythrocyte
Female
Humans
Infant
Male
Middle Aged
Pedigree
Phenotype
Spherocytosis, Hereditary
beta-Thalassemia

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