Article
High prevalence of the point mutation in exon 6 of the xeroderma pigmentosum group A-complementing (XPAC) gene in xeroderma pigmentosum group A patients in Tunisia.
American journal of human genetics - 1 Nov 1993
Nishigori C, Zghal M, Yagi T, Imamura S, Komoun M R, Takebe H
Abstract excerpt
Xeroderma pigmentosum (XP) patients in Tunisia who belong to the genetic complementation group A (XPA) have milder skin symptoms than do Japanese XPA patients. Such difference in the clinical features might be caused by the difference in the site of mutation in the XP A-complementing (XPAC) gene....
Topics
- Adolescent
- Adult
- Base Sequence
- Cells, Cultured
- Child
- DNA Primers
- DNA Repair
- Exons
- Genetic Complementation Test
- Humans
- Introns
- Molecular Sequence Data
- Phenotype
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Prevalence
- Tunisia