Article
Two new polymorphisms in introns 2 and 3 of the human porphobilinogen deaminase gene.
Human genetics - 1 Sept 1993
Daimon M, Morita Y, Yamatani K, Igarashi M, Fukase N, Ohnuma H, Sugiyama K, Ogawa A, Manaka H, Tominaga M
Abstract excerpt
Sequencing of the polymerase chain reaction amplified exon 2-4 fragment of the human porphobilinogen deaminase gene revealed a G/T polymorphism (I2G and I2T) in intron 2, and a G/A polymorphism (I3G and I3A) in intron 3 of the gene. The frequencies of these alleles are presented.
Topics
- Alleles
- Base Sequence
- Chromosomes, Human, Pair 11
- Gene Frequency
- Humans
- Hydroxymethylbilane Synthase
- Introns
- Japan
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length