Article
Locus heterogeneity of autosomal dominant long QT syndrome.
The Journal of clinical investigation - 1 Aug 1993
Curran M, Atkinson D, Timothy K, Vincent G M, Moss A J, Leppert M, Keating M
Abstract excerpt
Autosomal dominant long QT syndrome (LQT) is an inherited disorder that causes syncope and sudden death from cardiac arrhythmias. In genetic linkage studies of seven unrelated families we mapped a gene for LQT to the short arm of chromosome 11 (11p15.5), near the Harvey ras-1 gene (H ras-1). To determine if the same locus was responsible for LQT in additional families, we performed linkage studies with DNA...
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