The DM mutation; diagnostic applications in the Finnish population.

doi:10.1111/j.1399-0004.1993.tb04446.x

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Article

The DM mutation; diagnostic applications in the Finnish population.

Clinical genetics - 1 Apr 1993

Nokelainen P, Shelbourne P, Shaw D, Brook J D, Harley H G, Johnson K, Somer H, Savontaus M L, Peltonen L

Abstract excerpt

A pair of marker loci, D19S63 and D19S51, which are tightly linked to the myotonic dystrophy (DM) locus, were used to evaluate diagnostic applicability in the Finnish population. Results were then compared to direct detection of the mutation. The D19S63 locus revealed a linkage disequilibrium, si...

Topics

Alleles
Blotting, Southern
DNA
Electromyography
Female
Finland
Gene Frequency
Genetic Carrier Screening
Genetic Linkage
Genetic Markers
Haplotypes
Humans
Lod Score
Male
Muscles
Mutation
Myotonic Dystrophy
Pedigree

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