Article
Analysis of uroporphyrinogen decarboxylase complementary DNAs in sporadic porphyria cutanea tarda.
Gastroenterology - 1 Jul 1993
Garey J R, Franklin K F, Brown D A, Harrison L M, Metcalf K M, Kushner J P
Abstract excerpt
BACKGROUND: Sporadic porphyria cutanea tarda (S-PCT) has been considered an acquired disease because of the generation of liver-specific inhibitors of uroporphyrinogen decarboxylase (URO-D) activity. Several families have been described with S-PCT in multiple generations, raising the possibility...
Topics
- Adult
- Aged
- Base Sequence
- DNA
- Female
- Humans
- Liver
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Porphyria Cutanea Tarda
- Uroporphyrinogen Decarboxylase