Article
Analysis of uroporphyrinogen decarboxylase complementary DNAs in sporadic porphyria cutanea tarda.
Gastroenterology - 1 Jul 1993
Garey J R, Franklin K F, Brown D A, Harrison L M, Metcalf K M, Kushner J P
Abstract excerpt
BACKGROUND: Sporadic porphyria cutanea tarda (S-PCT) has been considered an acquired disease because of the generation of liver-specific inhibitors of uroporphyrinogen decarboxylase (URO-D) activity. Several families have been described with S-PCT in multiple generations, raising the possibility of an inherited basis for the disease. To determine if S-PCT is associated with mutant URO-Ds that might be sensitive...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.