A connexin-32 mutation associated with Charcot-Marie-Tooth disease does not affect channel formation in oocytes.

doi:10.1016/0014-5793(94)00819-1

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Article

A connexin-32 mutation associated with Charcot-Marie-Tooth disease does not affect channel formation in oocytes.

FEBS letters - 29 Aug 1994

Rabadan-Diehl C, Dahl G, Werner R

Abstract excerpt

Members of the connexin family differ most in their carboxy-termini, both with respect to sequence and length. In order to assess the contribution of this region to channel function, a series of carboxy-terminal deletion mutants were tested in the paired-oocyte expression system. Connexin-32 can...

Topics

Amino Acid Sequence
Charcot-Marie-Tooth Disease
Connexins
Gap Junctions
Humans
Molecular Sequence Data
Mutation
Oocytes
Gap Junction beta-1 Protein

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