[Cardiomyopathies from the aspect of molecular cardiology].

Abstract excerpt

Methods of molecular cardiology have extended our knowledge of cardiomyopathies. In hypertrophic cardiomyopathy the existence of at least nine beta-myosin heavy chain gene mutations on the arm of the 14th chromosome were detected. The latter cause substitution of amino acids in the molecule of this protein with subsequent slowing of the actin shift against myosin during muscle contractions. The presence of...

Topics

• Cardiomyopathy, Dilated
• Cardiomyopathy, Hypertrophic
• Humans
• Mutation
• Myosins
• Point Mutation