[Atypical presentation of Leber's optic neuropathy].

doi:10.1055/s-2008-1035568

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Article

[Atypical presentation of Leber's optic neuropathy].

Klinische Monatsblatter fur Augenheilkunde - 1 May 1994

Borruat F X, Sanders M D

Abstract excerpt

BACKGROUND: Leber's optic neuropathy (LON) is the phenotypic expression of an inherited disorder due to a mitochondrial DNA mutation. Numerous loci of a point mutation in the mitochondrial genome are reported: 3460, 4160, 11778, 14484 and, 15257. Typically visual loss occurs in young males and a...

Topics

Adult
DNA, Mitochondrial
Diagnosis, Differential
Female
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Mutation
Optic Atrophies, Hereditary
Optic Nerve
Phenotype

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