Article
Multilocus DNA fingerprinting: the independence problem in quantitative paternity testing.
Electrophoresis - 1 Feb 1994
Krawczak M
Abstract excerpt
A simulation study was performed in order to determine whether or not the assumption of independence, made in the quantitative analysis of multilocus DNA fingerprints, represents an inadmissible over-simplification. A total of 10,000 cases of true and false paternity, respectively, were simulated in twenty replicas of various genetic models. Log-likelihood ratios (paternity vs. non-paternity; LR) were calculated...
Topics
- Chromosome Mapping
- Computer Simulation
- DNA Fingerprinting
- Genotype
- Humans
- Likelihood Functions
- Logistic Models
- Male
- Models, Genetic
- Paternity
- Predictive Value of Tests
- Reproducibility of Results