Hereditary arthro-ophthalmopathy (Stickler syndrome): a diagnosis to consider in familial premature osteoarthritis.

doi:10.1093/rheumatology/33.12.1175

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Article

Hereditary arthro-ophthalmopathy (Stickler syndrome): a diagnosis to consider in familial premature osteoarthritis.

British journal of rheumatology - 1 Dec 1994

Rai A, Wordsworth P, Coppock J S, Zaphiropoulos G C, Struthers G R

Abstract excerpt

A number of factors contribute to the pathogenesis of osteoarthritis. Genetic factors are predominant in some cases, including the syndrome of hereditary arthro-ophthalmopathy. The clinical features of the syndrome and the concept of genetic mutations in matrix components are discussed.

Topics

Adult
Aged
Collagen
Eye Diseases
Family Health
Female
Humans
Male
Mutation
Osteoarthritis
Pedigree
Phenotype
Syndrome

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