Importance of Lp(a) lipoprotein and HLA genotypes in atherosclerosis and diabetes.

doi:10.1111/j.1399-0004.1994.tb04201.x

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Article

Importance of Lp(a) lipoprotein and HLA genotypes in atherosclerosis and diabetes.

Clinical genetics - 1 Jul 1994

Dahlén G H, Slunga L, Lindblom B

Abstract excerpt

Lp(a) lipoprotein [Lp(a)] was found in previous studies to be independently associated with early atherosclerosis and its sequelae. Lp(a) in vitro bound to glucosaminoglycans and was easily aggregated at physiological Ca2+ concentration, and small Lp(a) aggregates were phagocytosed by macrophages...

Topics

Arteriosclerosis
Case-Control Studies
Diabetes Mellitus
Female
Genotype
HLA Antigens
Humans
Lipoprotein(a)
Male
Middle Aged

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