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Article

[The level of spontaneous genomic mutations in the somatic cells of human embryos].

TSitologiia i genetika - 1 Jan 2000

Lozyns'ka M R, Hnateĭko O Z, Havryliuk Iu I

Abstract excerpt

The study of the level of spontaneous genomic mutations in some human medical abortuses has demonstrated the intertissular variability in frequencies of polyploidies and endoreduplications in somatic cells of embryos. In fibroblasts they are encountered more frequently than in lymphoid cells. In the process of culturing in vitro the number of polypoidies and endoreduplications increases with passages. The...

Topics

Cells, Cultured
Embryo, Mammalian
Female
Fibroblasts
Genome, Human
Gestational Age
Humans
Lymphocytes
Metaphase
Mutation
Polyploidy
Pregnancy

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Pregnancy Trimester, First

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Identifiers

PMID: 7974788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7974788-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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