Fertilization and early embrology: Monozygotic twinning in the human is associated with the zona pellucida architecture

Abstract excerpt

Six cases of identical twin pregnancies which occurred in 2163 cycles of in-vitro fertilization during a 3 year period are reported. Monozygosity was confirmed when the number of fetuses exceeded the number of embryos replaced (n = 4) or when two concepti were observed in a single amniotic sac (n = 2). Each of the reported pregnancies resulted from replacement of embryos either with naturally thin zonae...

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