A case-control family history study of autism.

doi:10.1111/j.1469-7610.1994.tb02300.x

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Article

A case-control family history study of autism.

Journal of child psychology and psychiatry, and allied disciplines - 1 Jul 1994

Bolton P, Macdonald H, Pickles A, Rios P, Goode S, Crowson M, Bailey A, Rutter M

Abstract excerpt

Family history data on 99 autistic and 36 Down's syndrome probands are reported. They confirmed a raised familial loading for both autism and more broadly defined pervasive developmental disorders in siblings (2.9% and 2.9%, respectively, vs 0% in the Down's group) and also evidence for the famil...

Topics

Adolescent
Adult
Autistic Disorder
Case-Control Studies
Child
Child, Preschool
Congenital Abnormalities
Down Syndrome
Female
Humans
Intelligence
Male
Models, Genetic
Personality Assessment
Phenotype
Risk Factors

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