Article
Maintenance of genetic variability in a specific pathogen-free breeding colony.
Laboratory animal science - 1 Jun 1994
Ely J J, Manis G S, Keeling M E, Stone W H
Abstract excerpt
We used 18 genetic loci including blood groups, isozymes, and a serum protein to evaluate our efforts to preserve genetic variability in a specific pathogen-free (SPF) colony of rhesus monkeys. We compared genetic variability in the SPF population to the virally contaminated, non-SPF population from which it was derived. There was no change in the average gene diversity between the SPF and non-SPF populations....
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