An unreported RFLP for probe 218 EP6 that is useful in linkage analysis of adult polycystic kidney disease.

doi:10.1007/BF01247352

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Article

An unreported RFLP for probe 218 EP6 that is useful in linkage analysis of adult polycystic kidney disease.

Human genetics - 1 Oct 1993

Jeffery S, Morgan S

Abstract excerpt

Probe 218 EP6 is known to recognise two restriction fragment length polymorphisms (RFLPs) after digestion of genomic DNA with PvuII. We report a rare allele that segregates in Mendelian fashion, in a family where adult polycystic kidney disease was being tracked using linked polymorphisms.

Topics

Alleles
Chromosomes, Human, Pair 16
DNA
DNA Probes
Female
Genetic Linkage
Humans
Male
Pedigree
Polycystic Kidney, Autosomal Dominant
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length

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