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A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens.

28 Feb 1995

Abstract excerpt

Enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli O157:H7 are intestinal pathogens that profoundly damage the microvilli and subapical cytoskeleton of epithelial cells. Here we report finding in EPEC a 35-kbp locus containing several regions implicated in formation of these lesions. DNA probes throughout this locus hybridize to E. coli O157:H7 and other pathogens of three genera that cause...

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PMID: 7878036
DOI: 10.1073/pnas.92.5.1664

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