Article
A developmental-genetic model of alcoholism: implications for genetic research.
Journal of consulting and clinical psychology - 1 Dec 1994
Devor E J
Abstract excerpt
The research for biological-genetic markers of alcoholism is discussed in the context of a multifactorial, heterogeneous, developmental model of the disease. It is suggested that the strategies used in both linkage and association studies require modification to accommodate this more complex model. It is also suggested that several extant associations of genetic markers with alcoholism represent true secondary...
Topics
- Alcoholism
- Aldehyde Dehydrogenase
- Chromosomes, Human, Pair 11
- Genetic Markers
- Genotype
- Humans
- Isoenzymes
- Models, Genetic
- Monoamine Oxidase
- Phenotype
- Receptors, Dopamine D2
- Risk Factors