A gene for familial total anomalous pulmonary venous return maps to chromosome 4p13-q12.

Article

A gene for familial total anomalous pulmonary venous return maps to chromosome 4p13-q12.

American journal of human genetics - 1 Feb 1995

Bleyl S, Nelson L, Odelberg S J, Ruttenberg H D, Otterud B, Leppert M, Ward K

Abstract excerpt

Total anomalous pulmonary venous return (TAPVR) is a cyanotic congenital heart defect that, without surgical correction, has a high mortality rate in the first year of life. It usually occurs without a family history and has a low recurrence risk. However, we recently reported a large Utah-Idaho...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 4
Family
Female
Genetic Linkage
Genotype
Heart Defects, Congenital
Humans
Idaho
Lod Score
Male
Pedigree
Pulmonary Veins
Recombination, Genetic
Utah

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