A spontaneous hemadsorption-negative mutant of Mycoplasma pneumoniae exhibits a truncated adhesin-related 30-kilodalton protein and lacks the cytadherence-accessory protein HMW1.

Abstract excerpt

A spontaneous, hemadsorption-negative mutant of Mycoplasma pneumoniae lacks the cytoskeleton-forming HMW1 protein and exhibits a truncated adhesin-related 30-kDa protein. Genetic analyses revealed deletion of one nucleotide in the hmw1 gene and loss of eight repeated sequences comprising 144 nucleotides in the gene for the adhesin-related 30-kDa protein.

Topics

• Adhesins, Bacterial
• Bacterial Adhesion
• Bacterial Proteins
• Base Sequence
• Blotting, Southern
• Blotting, Western
• DNA, Bacterial
• Electrophoresis, Polyacrylamide Gel
• Molecular Sequence Data
• Molecular Weight
• Mutation