Article
Evidence of selection on PGM1 polymorphism in diabetic pregnancy.
Human biology - 1 Dec 1994
Gloria-Bottini F, Lucarini N, Borgiani P, Amante A, Gerlini G, La Torre M, Bottini E
Abstract excerpt
Ninety-nine pregnant women with insulin-dependent diabetes mellitus, 83 women with gestational diabetes, and a control sample of 315 nondiabetic consecutive puerperae have been studied along with their newborn infants. Neonatal macrosomia is less frequent among diabetic mothers with phosphoglucomutase (PGM1) genotype PGM1*1/*2 than among mothers with other PGM1 genotypes. In gestational diabetes the association...
Topics
- Adult
- Case-Control Studies
- Diabetes Mellitus, Type 1
- Diabetes, Gestational
- Female
- Fetal Macrosomia
- Genetic Carrier Screening
- Genotype
- Humans
- Incidence
- Infant, Newborn
